CephSmile V2.0 is software for 2D cephalometric analysis and focusing on orthodontics treatment planning and applied to simulate changes on the facial profile after receiving treatment. CephSmile could be used to analyze craniofacial growth changes that lead to skeletal discrepancies and to study the cause of malocclusions. CephSmile V2.0 is able to draw the cephalometric traces of lateral skull and face in both bones and soft surface sections using the landmarks defined by the dentists. Furthermore, this program calculates the sizes of angles and the distances to be used for cephalometric analysis. CephSmile can perform automatic drawing of the significant traces of face, skull, and teeth by using the reference points. CephSmile program provides tools that allow users to mark the correct points with ease. It also enable uses to perform cephalometric analysis with different types of analysis, such as Mahidol Analysis, Down Analysis, Steiner Analysis, Tweed Analysis, Jaraback Analysis, Harvold Analysis, Rickette Analysis, and McNamara Analysis which are the significant data that show the structural problems on skulls, face, and teeth. CephSmile V2.0 has main features as followings:

# Cephalometric Lateral Analysis

# Superimposition

# Orthodontic Treatment Simulation

# PA Analysis

# 3D Skull from 2D Projections

# 2D Digital Model Analysis & Planning

UNIQUENESS

CephSmile V2.0 has been developed for analyzing the lateral cephalometric radiographs, postero-anterior cephalometric radiographs and a dental model photograph to facilitate the orthodontic treatment planning to be faster than before. The uniqueness of this program consistes of three key features to be described as follows:

# Six national cephalometric analyses such as Mahidol, Chula, Chiang Mai, Songkla, Songkla Othognathic, and Khonkaen analysis along with nine international cephalometric analyses such as Down, Steiner, Tweed, Jarabak, Harvold, Ricketts, McNamara, ABO and Sassouni Analysis.
# Local contrast enhancement function on radiographic images to facilitate the overlaying and landmarking process.
# Zoom function on radiographic image with trace lines using interpolating technique to reduce the artifacts on the magnified images of trace lines and the X-ray image.
# Deformable template fitting along with smooth function to allow trace lines to be in line the soft and hard tissue trace lines on radiographic images.
# Color displays numeric results of Cephalometric analysis which can be changed if modifying the norms and/or standard deviations. CephSmileV2

# Displacement ratio between hard and soft tissue derived from the statistic data from the area under the nose to the chin from 50 Thai patients who had received orthodontic treatments.
# Thin plate spline technique to change the facial area by weighting and spline factors calculated from the paired positions of trace lines and paired landmarks before and after the landmark and traceline movement.

# Matching landmarks and trace lines from a lateral image with the corresponding landmarks and trace lines from a PA image.
# Applying the matched landmark and trace lines with the 3D skull model before applying 3D Thin place spline to morph the 3D skull model verified by linear and angular measurements.